SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05684

Signal sequence   MGRFIFVSFGLLVVFVSLSGTGA

Length  23

Organism  Gloydius brevicauda (Korean slamosa snake) (Agkistrodon halys brevicaudus)

UniProt ID  Q9YGN4,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05684.cif

Structure  SPKB05684.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2404.89584

Aliphatic index  122.6086957

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -5.23733

Hydropathy 



Literature Information


Title  Purification and cDNA cloning of salmorin that inhibits fibrinogen clotting.

DOI  10.1016/s0049-3848(00)00260-7,

Publication Year  2000

PubMed ID  10963789,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.