SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05668

Signal sequence   METLLLTLLVVTIVCLDLGYT

Length  21

Organism  Naja naja (Indian cobra)

UniProt ID  Q9PTT0,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05668.cif

Structure  SPKB05668.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2323.87204

Aliphatic index  190

Isoelectric point  3.550065682

Charge (pH=7)   -2.062619224

Topological polar surface area  821.07

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.4436

Hydropathy 



Literature Information


Title  Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.

DOI  10.1021/bi00060a002,

Publication Year  1993

PubMed ID  8443154,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.