General Information
SPKB ID SPKB05666
Signal sequence MRGLAVLLLVACFCSVAFG
Length 19
Organism Theromyzon tessulatum (Duck leech)
UniProt ID Q9NBW4,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05666.cif
Physicochemical Information
Molecular weight 1970.47994
Aliphatic index 143.6842105
Isoelectric point 8.231408964
Charge (pH=7) 0.874031556
Topological polar surface area 669.25
Aromaticity 0.105263158
Average rotatable bonds 3.263157895
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 25
X logP energy -3.04673
Hydropathy
Literature Information
Title Therostasin, a novel clotting factor Xa inhibitor from the rhynchobdellid leech, Theromyzon tessulatum.
Publication Year 2000
PubMed ID 10852926,
Patent ID NA,