SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05662

Signal sequence   MVSIKSVLAAATAVSSALAAPFDFVPRDNSTALQAR

Length  36

Organism  Humicola insolens (Soft-rot fungus)

UniProt ID  Q9HGE1,

Motif  1..36



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05662.cif

Structure  SPKB05662.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3677.23364

Aliphatic index  100.5555556

Isoelectric point  9.690158308

Charge (pH=7)   0.998575611

Topological polar surface area  1516.45

Aromaticity  0.055555556

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  52

X logP energy  -17.92636

Hydropathy 



Literature Information


Title  Expression and processing of a major xylanase (XYN2) from the thermophilic fungus Humicola grisea var. thermoidea in Trichoderma reesei.

DOI  10.1046/j.1472-765x.2002.01057.x,

Publication Year  2002

PubMed ID  11849507,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.