SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05659

Signal sequence   MGRFIFVSFGLLVVFLSLSGTGA

Length  23

Organism  Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)

UniProt ID  Q9DEA1,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3BX4,

Predicted Structure ID  SPKB05659.cif

Structure  SPKB05659.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2418.92264

Aliphatic index  126.9565217

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.84723

Hydropathy 



Literature Information


Title  How does agkicetin-C bind on platelet glycoprotein Ibalpha and achieve its platelet effects?

DOI  10.1016/j.toxicon.2004.11.017,

Publication Year  2005

PubMed ID  15777951,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.