SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05651

Signal sequence   ITACLVLIGTVCA

Length  13

Organism  Centruroides noxius (Mexican scorpion)

UniProt ID  Q94435,

Motif  <1..13



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05651.cif

Structure  SPKB05651.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1276.61534

Aliphatic index  180

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  452.98

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  18

X logP energy  -2.9953

Hydropathy 



Literature Information


Title  An insect-specific toxin from Centruroides noxius Hoffmann. cDNA, primary structure, three-dimensional model and electrostatic surface potentials in comparison with other toxin variants.

DOI  10.1111/j.1432-1033.1996.0235r.x,

Publication Year  1996

PubMed ID  8973638,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.