General Information
SPKB ID SPKB05649
Signal sequence MILLSLYLCLAAMLHQSEG
Length 19
Organism Heloderma horridum horridum (Mexican beaded lizard)
UniProt ID Q91055,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05649.cif
Physicochemical Information
Molecular weight 2106.58424
Aliphatic index 154.2105263
Isoelectric point 5.361016533
Charge (pH=7) -0.972156617
Topological polar surface area 756.88
Aromaticity 0.052631579
Average rotatable bonds 3.684210526
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 29
X logP energy -3.4164
Hydropathy 
Literature Information
Title Isolation and characterization of helothermine, a novel toxin from Heloderma horridum horridum (Mexican beaded lizard) venom.
DOI 10.1016/0041-0101(90)90065-f,
Publication Year 1990
PubMed ID 1693019,
Patent ID NA,
