SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05647

Signal sequence   MAMSLKKIGAIAVGGAMVASALASGVMA

Length  28

Organism  Methanothermococcus thermolithotrophicus (Methanococcus thermolithotrophicus)

UniProt ID  Q8X235,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05647.cif

Structure  SPKB05647.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2607.24184

Aliphatic index  115.3571429

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  961.75

Aromaticity  0

Average rotatable bonds  3.178571429

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  38

X logP energy  -9.4276

Hydropathy 



Literature Information


Title  Genes and derived amino acid sequences of S-layer proteins from mesophilic, thermophilic, and extremely thermophilic methanococci.

DOI  10.1007/s00792-001-0264-1,

Publication Year  2002

PubMed ID  12382110,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.