SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05643

Signal sequence   MNLIIYVTIIALTSA

Length  15

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  Q8T4J9,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05643.cif

Structure  SPKB05643.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1636.02264

Aliphatic index  188.6666667

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  594.73

Aromaticity  0.066666667

Average rotatable bonds  3.466666667

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  22

X logP energy  -2.5114

Hydropathy 



Literature Information


Title  Pupal cuticle proteins of Manduca sexta: characterization and profiles during sclerotization.

DOI  10.1016/s0965-1748(99)00091-0,

Publication Year  2000

PubMed ID  10646967,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.