SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05635

Signal sequence   MGLTEIMLVLVSLAFVATAAA

Length  21

Organism  Ixodes scapularis (Black-legged tick) (Deer tick)

UniProt ID  Q8MUP7,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05635.cif

Structure  SPKB05635.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2121.62164

Aliphatic index  158.0952381

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  743.31

Aromaticity  0.047619048

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -3.6087

Hydropathy 



Literature Information


Title  A novel family of anticoagulants from the saliva of Ixodes scapularis.

DOI  10.1046/j.1365-2583.2002.00375.x,

Publication Year  2002

PubMed ID  12421422,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.