General Information
SPKB ID SPKB05635
Signal sequence MGLTEIMLVLVSLAFVATAAA
Length 21
Organism Ixodes scapularis (Black-legged tick) (Deer tick)
UniProt ID Q8MUP7,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05635.cif
Physicochemical Information
Molecular weight 2121.62164
Aliphatic index 158.0952381
Isoelectric point 3.849983241
Charge (pH=7) -1.000240578
Topological polar surface area 743.31
Aromaticity 0.047619048
Average rotatable bonds 3.238095238
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 28
X logP energy -3.6087
Hydropathy
Literature Information
Title A novel family of anticoagulants from the saliva of Ixodes scapularis.
DOI 10.1046/j.1365-2583.2002.00375.x,
Publication Year 2002
PubMed ID 12421422,
Patent ID NA,