SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05634

Signal sequence   MKLFVLAAVLGVCLA

Length  15

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  Q8MUC5,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05634.cif

Structure  SPKB05634.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1548.02104

Aliphatic index  182

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  496.74

Aromaticity  0.066666667

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  19

X logP energy  0.0836

Hydropathy 



Literature Information


Title  Pupal cuticle proteins of Manduca sexta: characterization and profiles during sclerotization.

DOI  10.1016/s0965-1748(99)00091-0,

Publication Year  2000

PubMed ID  10646967,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.