SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05632

Signal sequence   MAGPAMLVAAALALCLLLASPGLA

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  Q8MJV4,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05632.cif

Structure  SPKB05632.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2238.83344

Aliphatic index  159.1666667

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  735.27

Aromaticity  0

Average rotatable bonds  2.833333333

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -3.6099

Hydropathy 



Literature Information


Title  Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.

DOI  10.1074/jbc.M205883200,

Publication Year  2002

PubMed ID  12118011,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.