SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05631

Signal sequence   MGARGPGPGATARRRLLALLLLLLLLPLPARA

Length  32

Organism  Sus scrofa (Pig)

UniProt ID  Q8MI35,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05631.cif

Structure  SPKB05631.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3319.15104

Aliphatic index  152.8125

Isoelectric point  13.10207708

Charge (pH=7)   4.997967743

Topological polar surface area  1259.99

Aromaticity  0

Average rotatable bonds  3.28125

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  40

X logP energy  -7.94575

Hydropathy 



Literature Information


Title  Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.

DOI  10.1074/jbc.M205337200,

Publication Year  2002

PubMed ID  12130646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.