SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05630

Signal sequence   MIVFIVLPILAAVLQQSSG

Length  19

Organism  Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi)

UniProt ID  Q8JI40,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05630.cif

Structure  SPKB05630.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1999.48264

Aliphatic index  179.4736842

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  704.97

Aromaticity  0.052631579

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -2.9419

Hydropathy 



Literature Information


Title  Cloning and characterization of novel snake venom proteins that block smooth muscle contraction.

DOI  10.1046/j.1432-1033.2002.02940.x,

Publication Year  2002

PubMed ID  12047379,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.