SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05622

Signal sequence   MNYLITISLALLLMTGVASG

Length  20

Organism  Androctonus amoreuxi (African fattail scorpion) (Scorpio amoreuxi)

UniProt ID  Q86SE0,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05622.cif

Structure  SPKB05622.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2081.55664

Aliphatic index  161

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  760.46

Aromaticity  0.05

Average rotatable bonds  3.4

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -5.0331

Hydropathy 



Literature Information


Title  Isolation of scorpion (Androctonus amoreuxi) putative alpha neurotoxins and parallel cloning of their respective cDNAs from a single sample of venom.

DOI  10.1016/s0167-0115(03)00146-0,

Publication Year  2003

PubMed ID  12972326,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.