SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05621

Signal sequence   MNYLVMISLALLFMIGVES

Length  19

Organism  Androctonus amoreuxi (African fattail scorpion) (Scorpio amoreuxi)

UniProt ID  Q86SD9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05621.cif

Structure  SPKB05621.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2144.67364

Aliphatic index  158.9473684

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  728.2

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  28

X logP energy  -1.4603

Hydropathy 



Literature Information


Title  Isolation of scorpion (Androctonus amoreuxi) putative alpha neurotoxins and parallel cloning of their respective cDNAs from a single sample of venom.

DOI  10.1016/s0167-0115(03)00146-0,

Publication Year  2003

PubMed ID  12972326,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.