SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05620

Signal sequence   MTRFSLTVLAVLAACFGSNIRPNVA

Length  25

Organism  Dermatophagoides farinae (American house dust mite)

UniProt ID  Q86R84,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05620.cif

Structure  SPKB05620.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2652.16824

Aliphatic index  113.2

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1043.83

Aromaticity  0.08

Average rotatable bonds  3.32

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  36

X logP energy  -10.40506

Hydropathy 



Literature Information


Title  Identification, characterization, and cloning of a complementary DNA encoding a 60-kd house dust mite allergen (Der f 18) for human beings and dogs.

DOI  10.1067/mai.2003.1602,

Publication Year  2003

PubMed ID  12847483,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.