SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05616

Signal sequence   MIAFTLLSLAAVLQQSFG

Length  18

Organism  Ophiophagus hannah (King cobra) (Naja hannah)

UniProt ID  Q7ZT98,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05616.cif

Structure  SPKB05616.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1910.30184

Aliphatic index  141.1111111

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  704.89

Aromaticity  0.111111111

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -4.6476

Hydropathy 



Literature Information


Title  Wide distribution of cysteine-rich secretory proteins in snake venoms: isolation and cloning of novel snake venom cysteine-rich secretory proteins.

DOI  10.1016/s0003-9861(03)00028-6,

Publication Year  2003

PubMed ID  12646276,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.