SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05614

Signal sequence   MEQKRTLRVFLAVSLLCALANA

Length  22

Organism  Aplysia californica (California sea hare)

UniProt ID  Q7Z0T3,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05614.cif

Structure  SPKB05614.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2447.98304

Aliphatic index  133.1818182

Isoelectric point  9.828251175

Charge (pH=7)   1.93748305

Topological polar surface area  988.18

Aromaticity  0.045454545

Average rotatable bonds  3.772727273

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  33

X logP energy  -7.83886

Hydropathy 



Literature Information


Title  Characterization of Aplysia enticin and temptin, two novel water-borne protein pheromones that act in concert with attractin to stimulate mate attraction.

DOI  10.1074/jbc.M313585200,

Publication Year  2004

PubMed ID  15054104,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.