SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05606

Signal sequence   MKMKLVTAAVMGLAMSTAMA

Length  20

Organism  Legionella pneumophila

UniProt ID  Q70YI1,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05606.cif

Structure  SPKB05606.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2056.64474

Aliphatic index  93

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  728.95

Aromaticity  0

Average rotatable bonds  3.55

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  31

X logP energy  -5.478

Hydropathy 



Literature Information


Title  DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity.

DOI  10.1128/iai.57.4.1263-1270.1989,

Publication Year  1989

PubMed ID  2925252,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.