SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05601

Signal sequence   MGRFIFLSSGLLVVFLSLSGTGA

Length  23

Organism  Bitis arietans (African puff adder)

UniProt ID  Q6X5T3,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05601.cif

Structure  SPKB05601.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2372.85104

Aliphatic index  131.3043478

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  866.57

Aromaticity  0.130434783

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -6.70753

Hydropathy 



Literature Information


Title  Molecular cloning of disintegrin-like transcript BA-5A from a Bitis arietans venom gland cDNA library: a putative intermediate in the evolution of the long-chain disintegrin bitistatin.

DOI  10.1007/s00239-005-0268-z,

Publication Year  2006

PubMed ID  16786436,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.