SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05600

Signal sequence   MRPRCCILALVCWITVFLLQCSKG

Length  24

Organism  Homo sapiens (Human)

UniProt ID  Q6UXB1,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05600.cif

Structure  SPKB05600.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2754.48494

Aliphatic index  125.8333333

Isoelectric point  8.693497258

Charge (pH=7)   2.749783779

Topological polar surface area  972.99

Aromaticity  0.083333333

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  36

X logP energy  -4.97206

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.