SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05590

Signal sequence   MELKSGLSILLCFGICIAVINA

Length  22

Organism  Theromyzon tessulatum (Duck leech)

UniProt ID  Q6T6C2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05590.cif

Structure  SPKB05590.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2308.88104

Aliphatic index  164.0909091

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  821.29

Aromaticity  0.045454545

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -4.3843

Hydropathy 



Literature Information


Title  Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum.

DOI  10.1074/jbc.M312156200,

Publication Year  2004

PubMed ID  15102860,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.