SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05589

Signal sequence   MHAKIILALFLGMTAFLAVQA

Length  21

Organism  Theromyzon tessulatum (Duck leech)

UniProt ID  Q6T6C1,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05589.cif

Structure  SPKB05589.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2259.83954

Aliphatic index  149.047619

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  763.34

Aromaticity  0.095238095

Average rotatable bonds  3.523809524

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -1.5095

Hydropathy 



Literature Information


Title  Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum.

DOI  10.1074/jbc.M312156200,

Publication Year  2004

PubMed ID  15102860,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.