SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05579

Signal sequence   MALLPVVVFLITMLLPCVLTN

Length  21

Organism  Cavia porcellus (Guinea pig)

UniProt ID  Q60477,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05579.cif

Structure  SPKB05579.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2300.98824

Aliphatic index  190

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  711.29

Aromaticity  0.047619048

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  28

X logP energy  0.389

Hydropathy 



Literature Information


Title  Purification and characterization of the primary acrosomal autoantigen of guinea pig epididymal spermatozoa.

DOI  10.1095/biolreprod38.2.423,

Publication Year  1988

PubMed ID  3282555,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.