SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05578

Signal sequence   MKCFAQIVVLLLVIAFSHG

Length  19

Organism  Bombina orientalis (Oriental fire-bellied toad)

UniProt ID  Q5W280,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05578.cif

Structure  SPKB05578.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2089.62824

Aliphatic index  158.9473684

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  705.14

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -1.4847

Hydropathy 



Literature Information


Title  Molecular cloning of mRNA from toad granular gland secretion and lyophilized skin: identification of Bo8--a novel prokineticin from Bombina orientalis.

DOI  10.1016/j.peptides.2004.10.021,

Publication Year  2005

PubMed ID  15652643,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.