SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05577

Signal sequence   MKTLLLSPVVVTIVCLDLGYT

Length  21

Organism  Hydrophis peronii (Spiny-headed seasnake) (Acalyptophis peronii)

UniProt ID  Q5UFR8,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05577.cif

Structure  SPKB05577.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2278.83424

Aliphatic index  166.6666667

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  801

Aromaticity  0.047619048

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -3.4979

Hydropathy 



Literature Information


Title  Amino-acid sequence of the minor neurotoxin from Acalyptophis peronii venom.

DOI  10.1515/bchm3.1988.369.1.521,

Publication Year  1988

PubMed ID  3202959,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.