SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05576

Signal sequence   MKRTLMAFLLLGGLALA

Length  17

Organism  Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

UniProt ID  Q5SME3,

Motif  1..17



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05576.cif

Structure  SPKB05576.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1819.34034

Aliphatic index  155.2941176

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  637.07

Aromaticity  0.058823529

Average rotatable bonds  3.647058824

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  23

X logP energy  -1.72383

Hydropathy 



Literature Information


Title  Amino acid sequence of cytochrome c-552 from Thermus thermophilus HB8.

DOI  10.1016/0006-291x(85)90115-9,

Publication Year  1985

PubMed ID  2986626,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.