SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05573

Signal sequence   MKKTLLASSLAVGLGIVAGNAGHEAHA

Length  27

Organism  Staphylococcus aureus (strain COL)

UniProt ID  Q5HEA4,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05573.cif

Structure  SPKB05573.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2617.06164

Aliphatic index  115.9259259

Isoelectric point  9.541428347

Charge (pH=7)   1.180987536

Topological polar surface area  1070.4

Aromaticity  0

Average rotatable bonds  3.259259259

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -11.7611

Hydropathy 



Literature Information


Title  Extracellular proteins of Staphylococcus aureus and the role of SarA and sigma B.

DOI  10.1002/1615-9861(200104)1:4<480::AID-PROT480>3.0.CO;2-O,

Publication Year  2001

PubMed ID  11681202,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.