SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05572

Signal sequence   MALIILLVACLSVVSA

Length  16

Organism  Argas reflexus (European pigeon tick)

UniProt ID  Q5GQ85,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05572.cif

Structure  SPKB05572.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1616.09364

Aliphatic index  219.375

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  540.28

Aromaticity  0

Average rotatable bonds  3.25

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  21

X logP energy  -1.3579

Hydropathy 



Literature Information


Title  IgE-mediated anaphylaxis caused by bites of the pigeon tick Argas reflexus: cloning and expression of the major allergen Arg r 1.

DOI  10.1016/j.jaci.2004.11.052,

Publication Year  2005

PubMed ID  15753913,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.