SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05571

Signal sequence   MERKLALLLFLGMVTLASC

Length  19

Organism  Tityus costatus (Brazilian scorpion)

UniProt ID  Q5G8A6,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05571.cif

Structure  SPKB05571.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2109.67474

Aliphatic index  148.9473684

Isoelectric point  8.545125282

Charge (pH=7)   0.937486361

Topological polar surface area  752.8

Aromaticity  0.052631579

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.96263

Hydropathy 



Literature Information


Title  The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.

DOI  10.1016/j.toxicon.2004.10.014,

Publication Year  2005

PubMed ID  15683865,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.