SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05560

Signal sequence   KTLLLTLVVVTILCLDLGYT

Length  20

Organism  Ophiophagus hannah (King cobra) (Naja hannah)

UniProt ID  Q53B53,

Motif  <1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05560.cif

Structure  SPKB05560.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2191.73804

Aliphatic index  199.5

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  780.69

Aromaticity  0.05

Average rotatable bonds  3.55

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -2.4173

Hydropathy 



Literature Information


Title  Cloning and purification of alpha-neurotoxins from king cobra (Ophiophagus hannah).

DOI  10.1016/j.toxicon.2004.06.003,

Publication Year  2004

PubMed ID  15302536,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.