SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05556

Signal sequence   MKFSLACLLALAGLQAALA

Length  19

Organism  Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)

UniProt ID  Q4WZ11,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05556.cif

Structure  SPKB05556.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1905.38734

Aliphatic index  154.7368421

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  676.46

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -3.5355

Hydropathy 



Literature Information


Title  Biochemical properties and primary structure of elastase inhibitor AFUEI from Aspergillus fumigatus.

DOI  10.1099/jmm.0.47789-0,

Publication Year  2008

PubMed ID  18566136,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.