SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05555

Signal sequence   MEIQQTHRKINRPLVSLALVGALVSITPQQSHA

Length  33

Organism  Helicobacter pylori (Campylobacter pylori)

UniProt ID  Q48245,

Motif  1..33



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05555.cif

Structure  SPKB05555.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3637.26134

Aliphatic index  118.1818182

Isoelectric point  11.47972967

Charge (pH=7)   2.181275948

Topological polar surface area  1538.02

Aromaticity  0

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  51

X logP energy  -16.21296

Hydropathy 



Literature Information


Title  Purification and characterization of the vacuolating toxin from Helicobacter pylori.

DOI  NA,

Publication Year  1992

PubMed ID  1587837,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.