SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05554

Signal sequence   MKANKLSAITLCILGYAHTVYA

Length  22

Organism  Haemophilus ducreyi (strain 35000HP / ATCC 700724)

UniProt ID  Q47952,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05554.cif

Structure  SPKB05554.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2381.87684

Aliphatic index  120

Isoelectric point  9.276278024

Charge (pH=7)   2.024627778

Topological polar surface area  899.38

Aromaticity  0.090909091

Average rotatable bonds  3.5

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -6.3908

Hydropathy 



Literature Information


Title  Identification and purification of a conserved heme-regulated hemoglobin-binding outer membrane protein from Haemophilus ducreyi.

DOI  10.1128/iai.63.4.1241-1245.1995,

Publication Year  1995

PubMed ID  7890379,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.