General Information
SPKB ID SPKB05551
Signal sequence MKIKTLAIVVLSALSLSSTAALA
Length 23
Organism Escherichia coli
UniProt ID Q47223,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Fimbrium
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6Y7S,
Predicted Structure ID SPKB05551.cif
Physicochemical Information
Molecular weight 2301.85404
Aliphatic index 165.6521739
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 876.94
Aromaticity 0
Average rotatable bonds 3.391304348
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 33
X logP energy -7.46
Hydropathy
Literature Information
Title A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to suppress host cell apoptosis.
DOI 10.1016/j.molcel.2010.02.015,
Publication Year 2010
PubMed ID 20347420,
Patent ID NA,