General Information
SPKB ID SPKB05533
Signal sequence MDVVRTLILCVCLFGLTFA
Length 19
Organism Crassostrea virginica (Eastern oyster)
UniProt ID Q30HU9,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05533.cif
Physicochemical Information
Molecular weight 2114.65044
Aliphatic index 153.6842105
Isoelectric point 6.064584924
Charge (pH=7) -0.12552196
Topological polar surface area 726.78
Aromaticity 0.105263158
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 27
X logP energy -2.42783
Hydropathy
Literature Information
Title A novel slow-tight binding serine protease inhibitor from eastern oyster (Crassostrea virginica) plasma inhibits perkinsin, the major extracellular protease of the oyster protozoan parasite Perkinsus marinus.
DOI 10.1016/j.cbpb.2006.05.010,
Publication Year 2006
PubMed ID 16872855,
Patent ID NA,