SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05533

Signal sequence   MDVVRTLILCVCLFGLTFA

Length  19

Organism  Crassostrea virginica (Eastern oyster)

UniProt ID  Q30HU9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05533.cif

Structure  SPKB05533.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2114.65044

Aliphatic index  153.6842105

Isoelectric point  6.064584924

Charge (pH=7)   -0.12552196

Topological polar surface area  726.78

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -2.42783

Hydropathy 



Literature Information


Title  A novel slow-tight binding serine protease inhibitor from eastern oyster (Crassostrea virginica) plasma inhibits perkinsin, the major extracellular protease of the oyster protozoan parasite Perkinsus marinus.

DOI  10.1016/j.cbpb.2006.05.010,

Publication Year  2006

PubMed ID  16872855,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.