SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05532

Signal sequence   MSAWAALLLLWGLSLSPVTEQ

Length  21

Organism  Bos taurus (Bovine)

UniProt ID  Q2KJF1,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05532.cif

Structure  SPKB05532.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2286.71414

Aliphatic index  139.5238095

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  829.42

Aromaticity  0.095238095

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -4.0867

Hydropathy 



Literature Information


Title  Human CRISP-3 binds serum alpha(1)B-glycoprotein across species.

DOI  10.1016/j.bbagen.2010.01.011,

Publication Year  2010

PubMed ID  20116414,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.