General Information
SPKB ID SPKB05526
Signal sequence MAFHSLLLLCLAGLAFVSETAA
Length 22
Organism Macropus giganteus (Eastern gray kangaroo)
UniProt ID Q29616,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05526.cif
Physicochemical Information
Molecular weight 2278.75284
Aliphatic index 142.2727273
Isoelectric point 5.36107726
Charge (pH=7) -0.971306203
Topological polar surface area 801.09
Aromaticity 0.090909091
Average rotatable bonds 3.272727273
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 30
X logP energy -4.3931
Hydropathy 
Literature Information
Title Transthyretin expression evolved more recently in liver than in brain.
DOI 10.1016/0305-0491(93)90235-w,
Publication Year 1993
PubMed ID 8359020,
Patent ID NA,
