SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05524

Signal sequence   MKFTIIALCLALSLVGMTSS

Length  20

Organism  Trichosurus vulpecula (Brush-tailed possum)

UniProt ID  Q29143,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05524.cif

Structure  SPKB05524.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2099.63324

Aliphatic index  141.5

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  743.39

Aromaticity  0.05

Average rotatable bonds  3.5

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -5.2405

Hydropathy 



Literature Information


Title  A novel marsupial protein expressed by the mammary gland only during the early lactation and related to the Kunitz proteinase inhibitors.

DOI  10.1006/abbi.1996.0225,

Publication Year  1996

PubMed ID  8651704,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.