SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05521

Signal sequence   MRFPAKIVWLVLWTVCVA

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  Q28085,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05521.cif

Structure  SPKB05521.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2132.69924

Aliphatic index  140.5555556

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  688.96

Aromaticity  0.166666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  24

X logP energy  1.09487

Hydropathy 



Literature Information


Title  Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b.

DOI  10.1042/bj3150523,

Publication Year  1996

PubMed ID  8615824,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.