SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05519

Signal sequence   MQRVILVVLLLSCMAVLSVRA

Length  21

Organism  Aplysia californica (California sea hare)

UniProt ID  Q27441,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05519.cif

Structure  SPKB05519.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2314.97834

Aliphatic index  190

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  852.67

Aromaticity  0

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  30

X logP energy  -4.09666

Hydropathy 



Literature Information


Title  Identification and molecular cloning of a neuropeptide Y homolog that produces prolonged inhibition in Aplysia neurons.

DOI  10.1016/0896-6273(92)90188-j,

Publication Year  1992

PubMed ID  1524828,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.