SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05512

Signal sequence   MKELQITTGCLLLMVAAIGKTSA

Length  23

Organism  Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)

UniProt ID  Q25255,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05512.cif

Structure  SPKB05512.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2392.95634

Aliphatic index  127.3913043

Isoelectric point  8.540504393

Charge (pH=7)   0.937194639

Topological polar surface area  916.87

Aromaticity  0

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -7.722

Hydropathy 



Literature Information


Title  Characterization of a major peritrophic membrane protein, peritrophin-44, from the larvae of Lucilia cuprina. cDNA and deduced amino acid sequences.

DOI  10.1074/jbc.271.15.8925,

Publication Year  1996

PubMed ID  8621536,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.