General Information
SPKB ID SPKB05510
Signal sequence MKLFVLLCVFVLCLASQEKQQDRE
Length 24
Organism Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
UniProt ID Q24825,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05510.cif
Physicochemical Information
Molecular weight 2841.43784
Aliphatic index 121.6666667
Isoelectric point 6.310964863
Charge (pH=7) -0.122561782
Topological polar surface area 1107.96
Aromaticity 0.083333333
Average rotatable bonds 4.125
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 38
X logP energy -6.62043
Hydropathy
Literature Information
Title Amoebapores, a family of membranolytic peptides from cytoplasmic granules of Entamoeba histolytica: isolation, primary structure, and pore formation in bacterial cytoplasmic membranes.
DOI 10.1111/j.1365-2958.1994.tb01325.x,
Publication Year 1994
PubMed ID 7715451,
Patent ID NA,