General Information
SPKB ID SPKB05509
Signal sequence MRAIIFVLIFAIAFAATRE
Length 19
Organism Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
UniProt ID Q24824,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05509.cif
Physicochemical Information
Molecular weight 2153.65684
Aliphatic index 144.2105263
Isoelectric point 10.39777148
Charge (pH=7) 0.9997528
Topological polar surface area 768.45
Aromaticity 0.157894737
Average rotatable bonds 3.631578947
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 25
X logP energy -1.63596
Hydropathy 
Literature Information
Title Amoebapores, a family of membranolytic peptides from cytoplasmic granules of Entamoeba histolytica: isolation, primary structure, and pore formation in bacterial cytoplasmic membranes.
DOI 10.1111/j.1365-2958.1994.tb01325.x,
Publication Year 1994
PubMed ID 7715451,
Patent ID NA,
