SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05502

Signal sequence   MKKKVLKHCVILGILGTCLAGIGTGIKVDA

Length  30

Organism  Enterococcus hirae

UniProt ID  Q0Z8B6,

Motif  1..30



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05502.cif

Structure  SPKB05502.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3080.88594

Aliphatic index  139.6666667

Isoelectric point  10.22965355

Charge (pH=7)   3.963915273

Topological polar surface area  1143.76

Aromaticity  0

Average rotatable bonds  3.633333333

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  43

X logP energy  -7.5491

Hydropathy 



Literature Information


Title  Amino acid and nucleotide sequence, adjacent genes, and heterologous expression of hiracin JM79, a sec-dependent bacteriocin produced by Enterococcus hirae DCH5, isolated from Mallard ducks (Anas platyrhynchos).

DOI  10.1111/j.1574-6968.2007.00673.x,

Publication Year  2007

PubMed ID  17326750,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.