General Information
SPKB ID SPKB05501
Signal sequence MIRFKKTKLIASIAMALCLFSQPVISFS
Length 28
Organism Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)
UniProt ID Q0TUS0,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Cell membrane
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 1PFO,
Predicted Structure ID SPKB05501.cif
Physicochemical Information
Molecular weight 3144.92894
Aliphatic index 118.5714286
Isoelectric point 11.08111025
Charge (pH=7) 3.935121171
Topological polar surface area 1124.43
Aromaticity 0.107142857
Average rotatable bonds 3.785714286
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 42
X logP energy -6.53763
Hydropathy 
Literature Information
Title Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin.
DOI 10.1128/iai.56.12.3235-3240.1988,
Publication Year 1988
PubMed ID 2903128,
Patent ID NA,
