SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05496

Signal sequence   MQQQHLFRLNILCLSLMTALPAYA

Length  24

Organism  Neisseria meningitidis serogroup B

UniProt ID  Q09056,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05496.cif

Structure  SPKB05496.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2776.36854

Aliphatic index  126.25

Isoelectric point  8.534796248

Charge (pH=7)   1.026064949

Topological polar surface area  1047.46

Aromaticity  0.083333333

Average rotatable bonds  3.75

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -6.66163

Hydropathy 



Literature Information


Title  Cloning and characterization of Neisseria meningitidis genes encoding the transferrin-binding proteins Tbp1 and Tbp2.

DOI  10.1016/0378-1119(93)90348-7,

Publication Year  1993

PubMed ID  8344530,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.