SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05493

Signal sequence   MKAIVFVLIFAVAFAVTLRQ

Length  20

Organism  Entamoeba histolytica

UniProt ID  Q07831,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05493.cif

Structure  SPKB05493.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2237.81824

Aliphatic index  156

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  767.46

Aromaticity  0.15

Average rotatable bonds  3.6

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -0.98273

Hydropathy 



Literature Information


Title  Comparison of pore-forming peptides from pathogenic and nonpathogenic Entamoeba histolytica.

DOI  10.1016/0166-6851(93)90011-l,

Publication Year  1993

PubMed ID  8515772,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.