SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05489

Signal sequence   MFPRLIVWLLAASAVHAVLD

Length  20

Organism  Phlebotomus duboscqi (Sandfly)

UniProt ID  Q06K61,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05489.cif

Structure  SPKB05489.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2222.71974

Aliphatic index  161

Isoelectric point  7.550936504

Charge (pH=7)   0.089336563

Topological polar surface area  771.33

Aromaticity  0.1

Average rotatable bonds  3.35

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -1.19033

Hydropathy 



Literature Information


Title  Identification and characterization of a salivary adenosine deaminase from the sand fly Phlebotomus duboscqi, the vector of Leishmania major in sub-Saharan Africa.

DOI  10.1242/jeb.001289,

Publication Year  2007

PubMed ID  17297134,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.